* This calculator takes into account the most common and viable age-related chromosome conditions, including Trisomy 21 (Down syndrome), Trisomy 13 and Trisomy 18. These probability estimates do not include all chromosome conditions.
** The probabilities used in this calculator are based on maternal (mom’s) age at delivery, assuming natural conception and no use of a donor egg.
References: Hook EB, Cross PK, Schreinemachers DM. Chromosomal abnormality rates at amniocentesis and in live-born infants. JAMA. 1983 Apr 15;249(15):2034-8.
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